Which lifestyle factor is linked with an increased risk of colorectal cancer?

Obesity is linked with an increased risk of colorectal cancer due to several biological mechanisms. The excess adipose tissue, particularly visceral fat, can lead to the production of pro-inflammatory cytokines and hormones such as insulin and insulin-like growth factor-1 (IGF-1). These substances can promote cell proliferation and inhibit apoptosis, contributing to a higher likelihood of cancerous changes in the colorectal region. Furthermore, obesity often correlates with a sedentary lifestyle and poor dietary habits, which can compound the risk factors for developing colorectal cancer.

In contrast, maintaining a high level of physical activity, consuming a diet rich in fiber, and regularly incorporating vegetables into one’s diet are generally associated with protective factors against colorectal cancer. Physical activity helps regulate body weight and lowers inflammation, fiber intake is known to enhance bowel health and reduce carcinoma risk, and a vegetable-rich diet contributes essential nutrients and antioxidants that support cellular health. Therefore, these lifestyle factors do not increase the risk of colorectal cancer in the same way that obesity does.